Fmoc-Asp(OtBu)-(Dmb)Gly-OH
Supplier: BACHEM AMERICAS INC
4062763.0001
4062763.0005
B-4035.0001BAEA
515.34
USD
B-4035.0001BA
B-4035.0005BA
Fmoc-Asp(OtBu)-(Dmb)Gly-OH
Proteins and Peptides
Please see also the corresponding amino acid derivatives Fmoc-(Dmb)Ala-OH (B-4175), Fmoc-(Dmb)Gly-OH (B-4170), Fmoc-(Hmb)Gly-OH (B-3490), and Fmoc-(Dmb)Leu-OH (B-4165).
Dmb backbone protection completely prevents base-catalyzed aspartimide formation of the Asp(OtBu)-Gly motif during Fmoc-SPPS. The Dmb moiety is readily introduced by coupling this Fmoc-dipeptide. Contrary to the Hmb derivative, cyclic lactones cannot be formed during activation.
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