Fmoc-L-propargylglycine
Supplier: BACHEM AMERICAS INC
Synonyms:
Fmoc-Pra-OH, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine, N-Fmoc-L-propargylglycine, (S)-2-(Fmoc-amino)-4-pentynoic acid, Fmoc-propargyl-Gly-OH
Sequence: Fmoc-Pra-OH
Synonym(s): Fmoc-Propargyl-Gly-OH#(S)-2-(Fmoc-amino)-4-pentynoic acid
Bachem also offers resin-bound propargylglycine, Fmoc-Pra-Wang resin (D-2820).
Building block for the synthesis of precursor peptides for tritiation, and for "click chemistry". Pra-containing peptides have been modified by 1,3-dipolar cycloaddition, e.g. with alkyl azides. Peptides containing a Pra residue and an α-azido acid have been cyclized in the presence of CuBr/Na-ascorbate via triazole formation. Educt for the synthesis of Phe-derivatives by rhodium-catalyzed [2+2+2] cycloaddition.
Formula:
C₂₀H₁₇NO₄ MW: 335.359 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD01075095 CAS Number: 198561-07-8 |
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