Fmoc-Asp(ODmab)-OH
Supplier: BACHEM AMERICAS INC
Synonyms:
Fmoc-Asp(ODMAB)-OH
Sequence: Fmoc-Asp(ODmab)-OH
Asp-NH₂ is also called isoasparagine, so our Asp-NH₂ derivatives are assembled in the "Isoasparagine" subfamily.
Dmab can be removed with 2% hydrazine in DMF generating an indazole which allows the UV-spectrophotometrical monitoring of the cleavage. Conroy et al. used this Asp derivative for the solid-phase synthesis of N-linked glycopeptides. As Dmab represents an unhindered p-substituted Z-derivative, Asp(Dmab)-containing peptides are prone to base-catalyzed aspartimide formation.
Formula:
C₃₉H₄₂N₂O₈ MW: 666.771 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00797875 CAS Number: 269066-08-2 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...