Fmoc-Orn(Dde)-OH
Supplier: BACHEM AMERICAS INC
Sequence: Fmoc-Orn(Dde)-OH
Bachem also offers Fmoc-Orn(Boc)-Wang resin (D-1800).
The Nδ-protecting group Dde is orthogonal to both Fmoc and Boc which allows on-resin modification of ornithine side chains during Fmoc/tBu-based SPPS. The applications of Dde side-chain protection include synthesis of branched or di-epitopic peptides, preparation of MAP core molecules and lipo-MAPS, the synthesis of cyclic peptides, TASP molecules, and templates for combinatorial chemistry and synthetic proteins. Dde can be cleaved by 2% hydrazine in DMF.
Formula:
C₃₀H₃₄N₂O₆ Storage Temperature: Freezer |
MDL Number:
MFCD01862895 CAS Number: 269062-80-8 |
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