(Boc-Cys-OH)₂
Supplier: BACHEM AMERICAS INC
Synonyms:
N,N'-di-Boc-L-cystine, AK-32714, (Boc-Cys-OH)2, Bis-Boc-L-cystine, (Boc-Cystine-OH)₂
Sequence: (Boc-Cys-OH)₂
As the disulfide bond can be cleaved under mild conditions (e.g. with trialkylphosphines) cystine derivatives are highly economic educts for synthesizing Cys derivatives. The cystine derivatives of fluorophores (e.g. J-1175) or the pNA derivatives may be chosen as educts for synthesizing Cys substrates.
Tai et al. could obtain asymmetric cystine peptides from (Boc-Cys-OH)₂ by enzymatic catalysis with immobilized papain. Oxidation of Boc-cystine with hydrogen peroxide in the presence of Na wolframate yielded the sodium salt of Boc-cysteic acid. Boc cystine benzyl ester was used as educt for obtaining S-isoacyl dipeptide building blocks.
Formula:
C₁₆H₂₈N₂O₈S₂ MW: 440.526 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD00038250 CAS Number: 10389-65-8 EINECS: 233-852-9 |
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