(Gln²²)-beta-Amyloid (1-40) Trifluoroacetate
Supplier: BACHEM AMERICAS INC
4039928.0500
4039928.1000
H-6696.0500BAEA
474.73
USD
H-6696.0500BA
H-6696.1000BA
(Gln²²)-beta-Amyloid (1-40) Trifluoroacetate
Proteins and Peptides
The Dutch mutation (E22Q) of amyloid β-peptide aggregates more readily than the wild-type peptide and the resulting fibrils show increased neurotoxicity. The mutant peptide E22Q induced apoptosis of cerebral endothelial cells at a concentration of 25 μm, whereas WT Aβ 1-40 and the Italian mutant E22K (H-6698) showed no effect.
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