Acetyl-(D-Arg¹⁰,Cys¹¹,D-Phe¹⁴,Cys¹⁷)-beta-MSH (10-17) Amide Trifluoroacetate

Supplier: BACHEM AMERICAS INC

4049312.0001 4049312.0005
H-6268.0001BAEA 196.08 USD
H-6268.0001BA H-6268.0005BA
Acetyl-(D-Arg¹⁰,Cys¹¹,D-Phe¹⁴,Cys¹⁷)-beta-MSH (10-17) Amide Trifluoroacetate
Proteins and Peptides

Highly potent and selective β-MSH-derived melanocortin-4 receptor (MC-4R) agonist with sub-nanomolar potency. The binding affinities for human MC-4R, MC-1R, MC-3R and MC-5R were 0.55 ± 0.06, 16.78 ± 1.53, 56.79 ± 4.66, and < 500 nM, respectively. Daily subcutaneous injection of H-6268 to diet-induced obese rats over a period of 14 days demonstrated an effect on reduction of fat mass.

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