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The Function of mRNA in Biopharma Messenger RNA (mRNA) plays a critical role in gene expression a process in which stored genetic information in DNA is used to create proteins. This RNA molecule acts as an intermediary between the DNA and ribosome...

What Is Protein Aggregation? Protein aggregation is the phenomenon where proteins and biomolecules come together to form clusters or aggregates. These aggregates can manifest in various forms such as soluble and insoluble reversible and irreversib...

Solon Manufacturing Facility Our manufacturing facility in Solon OH include two buildings totaling 275000 sq. feet . Liquid manufacturing Liquid and aseptic processing Powder blending and processing Cleanroom liquid manufacturing and fill/finish C...

The Case for Peristaltic Pumps How operational and maintenance issues can ease with the right type of pump In real-world conditions pumps can be challenging. Some do not handle particulates some are difficult to use with high-viscosity materials o...

How to Select the Right Chromatography Resin Chromatography is a widely used technique in chemistry to separate a mixture by passing it in solution suspension or as a vapor through a medium that interacts with the mixture components moving them at...

What Is Protein Purification? Protein purification is an important technique in biochemistry molecular biology and biotechnology as proteins play a vital role in various biological processes. Proteins are one of the important macromolecules and ca...

Types of mass spectrometry Types of mass spectrometry Mass spectrometry is an analytical technique used to calculate the mass to charge ratio (m/z) of molecules within a sample. This can often be useful for determining the precise molecular weight...

Monoclonal Antibody Manufacturing Processes The monoclonal antibody manufacturing process plays an important role in producing therapeutic antibodies widely used in treating diseases such as cancer autoimmune disorders and other infectious disease...

The advent of digital imaging has transformed Western blot detection. Here we outline how Western blotting has changed and review qualities to look for in a digital imager. Chemiluminescence and fluorescence When most people think of imaging their...

Normalization is critical for obtaining accurate quantitative data from Western blots. Normalization accounts for unequal loading of samples across the lanes on a gel and for differences in transfer efficiency across a blot. Traditionally protein ...

Protein Sample Preparation for Mass Spectrometry Protein sample preparation In order to run a successful mass spectrometry analysis you will need to properly prepare your sample. This includes a number of steps that may be specialized depending on...

Three Types of Antibodies for Western Blot Types of antibodies for western blot In general various types of antibodies for western blot are used to detect and visualize specific proteins of interest. The primary antibodies are the key components t...

Downstream Processing Overview Downstream processing is an essential aspect of biotechnology particularly in the production of biopharmaceuticals. It includes the purification isolation and characterization of the target product from complex biolo...

Manufacturing CUSTOM CHEMICALS AND SERVICES SUPPORTING SCIENTIFIC ADVANCES FOR HUMAN HEALTH VWR Custom Manufacturing Services2 VWR enables the advancement of science by providing high-quality chemicals and services customized to your product or ma...

1 Determination of Pesticide Residues in Red Wine Using a QuEChERS Sample Preparation Approach and LC-MS/MS Detection Mike Oliver Thermo Scientific Runcorn UK This application presents a fast easy and cost-effective method for the determination of...

TITRATION THEORY AND PRACTICE 2 TITRATION THEORY AND PRACTICE The aim of this booklet is to explore titration from a historical theoretical and practical point of view dealing first with preset end-point titration then with inflection-point titrat...