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Case Study: Masterflex® Microflex® Pump Head Used for Applikon® miniBio Bioreactor This mini 500-mL bioreactor is currently being used for COVID-19 vaccine research Applikon Biotechnology is a global leader in developing and supplying advanced bio...

Upstream Processing Overview Upstream processing is an important stage in bioprocessing that involves preparing and manipulating biological materials before subjecting them to downstream processing. This step involves the development of viable cel...

Single-Use Technology in Cell and Gene Therapies Single-use technology (SUT) in cell and gene therapies has the transformative potential to revolutionize the treatment of various diseases. These therapies harness the power of cellular and genetic ...

Cell Culture Instruments VWR®'s cell culture portfolio provides all the essential instruments tailored to the needs of your cell biology processes enabling you to perform to rigorous levels of precision accuracy and reproducibility. Browse Cell Cu...

Cell culture Both autologous and allogeneic cells are obtained from donors utilizing methods including but not limited to apheresis aspirates and surgical biopsies. The donor cells of interest are processed to remove undesirable contaminants and p...

Fermentation media & supplements Depending on your expression system (e.g. microbial mammalian yeast or insect) maintaining cell viability is critical during applications – starting with modifications of the cell of interest through process develo...

Solutions for production We are committed to offering reliable and transparent supply chain solutions with our Custom Manufacturing Services designed to decrease the complexity you encounter. Our VWR Single-Use Solutions enable biopharmaceutical m...

Avantor OmniTop Sample Tubes® adjustable volume sampling system (AVSS) Enhance the effectiveness of your sampling process with the Avantor OmniTop Sample Tubes® adjustable volume sampling system (AVSS). Designed to precisely collect small volume s...

Upstream Cell Therapy Products & Solutions in Bioprocessing Compared to production volumes associated with other biologics (e.g. mAbs: 2000L to 10000L) cell therapy production volumes are more commonly between 1L to 10L. Even the quality parameter...

Upstream processing for mAbs Developing and manufacturing mAbs has moved away from a dependency on raw materials of animal origin. Our biochemical components and supplements are animal component-free to meet the needs of these applications. Produc...

Peristaltic Pump Technology Meets the Needs of Filling Applications Features and benefits inherent to peristaltic tubing pumps are well-known and backed up by years of trouble-free operation in a variety of applications across several industries. ...

Masterflex® case studies Case Study: A Sweet Success: Famous Maple Syrup Producer Enhances Production with Masterflex® B/T® Variable-Speed Pump Steve Rascher of Rascher's Sugar House in northern New York discovered he could enhance his production ...

CELLSTAR® Cell Culture Vessels Greiner Bio-One develops and distributes products for the cultivation storage and separation of cells and for specific applications in medical pharmaceutical and biotechnological research. The company’s product line ...

Upstream processing for microbial-based recombinant proteins Using microbial fermentation for the development and manufacture of recombinant proteins keeps on showing advantages e.g for the expression of proteins that do not require post-translati...

Shear-Sensitive Pumping with Peristaltic Pumps Factors Impacting Shear Sensitivity Peristaltic pumps have become the gold standard for shear-sensitive pumping applications where damage to cells or agitation of a suspension or colloidal mixture may...

Cell sensitive pumping with peristaltic pumps Ismatec Pro-280 pumphead for pumping living cells The Pro-280 pump head connected to either a BVP Process or MCP Process peristaltic pump drive is a suitable system to continuously pump living cells wh...