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Cycloheximide (microbial) ≥94%, white powder

Supplier: MP Biomedicals
Description: Applications
Cycloheximide is used in protein synthesis in apoptosis. It is also used in plant research to study disease resistance and as an ethylene stimulant, useful in studies involving fruit and leaf production.
Product Description
Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. It inhibits peptide synthesis in eukaryotic organisms but not in prokaryotes. Protein synthesis is blocked by the interaction of Cycloheximide with the translocase enzyme. This interaction prohibits the translocation of messenger RNA on the cytosolic, 80S ribosomes without inhibiting organelle protein synthesis.
Biochem/physiol Actions
Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.

Product Image-89150-312

Cycloheximide ≥95% (by TLC)

Supplier: Enzo Life Sciences
Description: Protein synthesis inhibitor

SDS

Product Image-76020-276

Cycloheximide, white powder cell culture reagent

Supplier: MP Biomedicals
Description: Cycloheximide is a glutarimide antibiotic derived from a microbial source. Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. Control of various molds and fungi in gelatin-based photographic emulsions, photoengraving glues, and other light-sensitive products is suggested.
Cycloheximide is used in plant research to study disease resistance and as an ethylene stimulant, useful in studies involving fruit and leaf production. It is also used in bacteriological media to isolate or count bacteria in the presence of yeast and molds; Used in protein synthesis in apoptosis; Gene expression; Glycogenolysis, gluconeogenesis and ureogenesis in isolated rat hepatocytes; Studies involving steroidogenesis; Used in plant regulation and as a quality control measure by the food and beverage industry.
Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors. Cycloheximide inhibits peptide synthesis in eukaryotic organisms but not in prokaryotes. Protein synthesis is blocked by the interaction of Cycloheximide with the translocase enzyme. This interaction prohibits the translocation of messenger RNA on the cytosolic, 80S ribosomes without inhibiting organelle protein synthesis. Cycloheximide is also known to induce FAS/FAS Ligand apoptosis, and triggers apoptosis in HL-60 cells, T-cell hybridomas, Burkitt's lymphoma cells in addition to a variety of other cell types. Cycloheximide will also delay or inhibit apoptosis induced by other agents.

Certificates

Product Image-TS35742-0250

Cycloheximide 95%

Supplier: Thermo Scientific Chemicals
Description: Cycloheximide 95%

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Cycloheximide 90%

Supplier: Thermo Scientific Chemicals
Description: A frequently used lab reagent that inhibits fungal growth by targeting protein synthesis.

Certificates

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Cycloheximide 100 mg/ml in DMSO, liquid

Catalog Number: (AAJ66004-XF)
Supplier: Thermo Scientific Chemicals
Description: Cycloheximide solution, 100mg/mL in DMSO, 0.2 micron filtered. Liquid.

SDS Certificates


Product Image-82021-600

Cycloheximide 100 mM

Catalog Number: (82021-600)
Supplier: G-Biosciences
Description: Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).
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Cycloheximide 95%, Ultrapure

Catalog Number: (AAJ66901-03)
Supplier: Thermo Scientific Chemicals
Description: Powder

SDS Certificates


Image Unavailable-100505-650

Cycloheximide

Catalog Number: (100505-650)
Supplier: R&D Systems
Description: Inhibitor of protein synthesis
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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