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Product Image-89147-914

AS601245 sum of isomers ≥95% (by HPLC)

Description: Jnk inhibitor
Catalog Number: 89147-914
Supplier: Enzo Life Sciences
Image Unavailable-77235-968

AS601245 98+%

Description: 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile, Purity: 98+%, CAS Number: 345987-15-7, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, Store in freezer, under -20 C, Size: 1mg
Catalog Number: 77235-968
Supplier: Ambeed
Image Unavailable-ALA275935100MG

AS601245 ≥95%, Moligand™

Description: Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.Product Introduction:A cell-permeable pyrimidinyl compound that displays anti-inflammatory properties. Acts as a potent, reversible, and ATP-competitive inhibitor of c-Jun N-terminal kinase (JNK, IC50 = 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respectively) with a 10- to 100-fold greater selectivity over a panel of 25 other commonly studied kinases (IC50 typically in the range of 1-10 µM or no effect at 10 µM). Its in vivo efficacy has been demonstrated in gerbils, mice, and rats via oral, i.v., or i.p. administration. Biochemical mechanism:Cell permeable: yesProduct competes with ATP.Primary TargethJNK 1, hJNK 2, hJNK 3Reversible: yesTarget IC50: 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respectively
Catalog Number: ALA275935100MG
Supplier: ALADDIN SCIENTIFIC

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