Cytochalasin D (from Zygosporium mansoni) ≥98% (by TLC), white solid, Sigma-Aldrich®

Supplier: MilliporeSigma

Synonyms: 7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-triene-1,17-dione 21(R)-acetate

250255-1MG
80055-214EA 244.27 USD
80055-214
Cytochalasin D (from Zygosporium mansoni) ≥98% (by TLC), white solid, Sigma-Aldrich®
Cytochalasin D

Cell-permeable fungal toxin


About 10-fold more potent than cytochalasin B (80055-212) in inhibiting actin filament function. Does not inhibit monosaccharide transport across cell membranes. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments. Inactivates low conductance K+channels. Also modulates CD4 cross-linking in T lymphocytes and increases intracellular Ca2+ levels. Exhibits antitumor activity.


Soluble in DMSO or EtOH

Formula: C₃₀H₃₇NO₆
MW: 507.63 g/mol
MDL Number: MFCD00077706
CAS Number: 22144-77-0

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