Anti-TNFR-I Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical
109-401-308S
76234-810EA 151.49 USD
76234-810
Anti-TNFR-I Rabbit Polyclonal Antibody
Antibodies
Tumor necrosis factor receptor superfamily member 1A (TNF p55 Receptor) is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. It contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

This antiserum against Human TNFMore Product Information
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