Anti-CD3e Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)) [clone: 145-2C11]

Supplier: BIOGEMS INTERNATIONAL INC.
05122-60-500
75841-736EA 464.55 USD
75841-736
Anti-CD3e Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)) [clone: 145-2C11]
Antibodies
The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specificMore Product Information
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